What are early signs and symptoms of the pre-icteric phase of hepatitis?

The early signs and symptoms of the pre-icteric phase of hepatitis are primarily characterized by nonspecific and systemic manifestations, which include fatigue, malaise, anorexia, and nausea/vomiting. During this phase, patients typically experience a general feeling of unwellness, accompanied by a decreased appetite and gastrointestinal symptoms. These manifestations occur before the onset of jaundice, which is a hallmark sign of the later stages of hepatitis.

Recognizing these early symptoms is crucial for timely diagnosis and management of hepatitis, as they may prompt further investigation into the underlying cause, whether it be viral, toxic, or autoimmune in nature. Understanding this phase helps in initiating appropriate interventions to support the patient even before more recognizable symptoms like jaundice appear.