What is one of the side effects of St. John's Wort?

St. John's Wort is known for its interaction with serotonin levels in the brain. This herbal supplement is often used for its potential antidepressant effects, but it can also have side effects that are important to consider. One significant side effect is the increased risk of serotonin syndrome, which can occur when there is an excess of serotonin activity in the brain. This risk can be heightened when St. John's Wort is taken alongside other medications that also increase serotonin levels, such as certain antidepressants.

Serotonin syndrome is characterized by symptoms such as confusion, agitation, rapid heart rate, fluctuating blood pressure, increased body temperature, and possibly seizures. It is a potentially life-threatening condition that requires immediate medical attention. Thus, understanding this side effect is crucial for safe clinical practice, especially for nurse practitioners who must manage complex medication regimens in their patients.

The other options mentioned do not accurately reflect the known side effects of St. John's Wort. While it may improve mood and help with anxiety and sleep in some patients, these effects do not outweigh the importance of being aware of the potential for serotonin syndrome when this herbal supplement is used in conjunction with other serotonergic agents.