What is the appropriate treatment for a patient with CMV who also has HIV?

The appropriate treatment for a patient with cytomegalovirus (CMV) who is also living with HIV is indeed ganciclovir. Ganciclovir is an antiviral medication specifically indicated for the treatment of CMV infections, especially in immunocompromised individuals, such as those with HIV/AIDS. Patients with HIV have a significantly weakened immune system, making them more susceptible to opportunistic infections, including CMV. Ganciclovir acts by inhibiting viral DNA synthesis, which helps to manage the viral load associated with CMV infections.

The other options do not effectively treat CMV. For instance, cefazolin is a cephalosporin antibiotic that targets bacterial infections, not viral infections like CMV. Ciprofloxacin is a fluoroquinolone antibiotic, also ineffective against viral pathogens. Fluconazole is an antifungal medication used primarily to treat fungal infections and has no efficacy against CMV. Therefore, ganciclovir is the most appropriate choice for managing CMV in a patient with an underlying HIV infection due to its specific action against this virus.